Granuloma Inguinale

Granuloma Inguinale is a disease, which is sexually transmitted and is resulted from bacterium called Calymmatobacterium Granulomatis, that causes chronic inflammation of the Granuloma Inguinalegenitals. Granuloma Inguinale is common in certain subtropical and tropical areas and occurs rarely in temperate climates. For example, in Northern of U.S, symptoms start about one to twelve weeks after getting infection.

The symptoms in the early stages include red, painless nodules, which slowly grow in the raised, round lumps. Infection sites include vagina, vulva and surrounding parts in women; and thighs, scrotum, and penis, in men. In both women and men, the face, buttocks, and anus can be infected. Usually, the raised lump can cover the genitals.

Healing process is slow and tissues scarring forms. Usually, the nodules become infected with other bacteria. If untreated, granuloma inguinale infection can spread throughout the person’s body to the liver, joints, or bones, resulting in anemia, fever, and significant weight loss.

Diagnosis of Granuloma Inguinale based on specific red bright lumps. To confirm diagnosis, microscopic testing of specimen obtained from the lump edge is performed. Treatment of Granuloma Inguinale consist of following antibiotics: Trimethoprim-Sulfamethoxazole, Streptomycin, Chloramphenicol, Erythromycin, and Tetracycline.

For six months after such treatment, the person must be monitored by a physician to be sure that Granuloma Inguinale is fully cured.

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