Colbenemid (probenecid, colchicines) is used for the treatment of long-term gouty arthritis when complicated by frequent, recurrent severe attacks of gout. Therapy with Colbenemid should begin when acute gout attack has subsided.

You should drink plenty of fluids to prevent blood in urine, and renal colic (sharp lower back pain produced by the passage of kidney stones), backbone pain, and uric acid stones, which are sometimes caused by Colbenemid. Sufficient sodium bicarbonate (antacid), or potassium citrate should also be taken to make the urine less acidic. Side effects such as, abdominal pain, fast heartbeat, tingling in the throat, anemia, blood in urine, diarrhea, fever, hair loss, headache, nausea, uric acid kidney stones, and skin inflammation may occur. You should contact your doctor if you experience any of these symptoms.

Colbenemid should not be prescribed if you ever had allergic reaction in the past or if you are sensitive to it. Treatment with this drug may aggravate the gout. In this case, your doctor may increase your dosage or prescribe another treatment option. People who have ever had peptic ulcers should take this medication with caution. If Colbenemid is taken with other certain drugs such as Tylenol, Ketamine, Ketoprofen, Lorazepam, Naproxen, penicillin, or Aspirin, effects of either can be decreased, increased or altered.

Patients should check with their doctor before combining these medications together. Women who are pregnant or plan to become pregnant or nursing should contact their doctor because Colbenemid may cause birth defects. The regular dose is one tablet, twice daily.

Use this medication exactly as prescribed and keep away from children.


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