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Idiopathic thrombocytopenic purpura is a medical condition, where low platelets counts with no discernible causes result in abnormal bleeding. The causes of platelets deficiency cure is not known, but autoimmune reaction, in which antibodies destroy an individual’s own platelets, appear to be involved. Although the bone marrow increases the production of platelets to compensate for the destructions, the supplies may not keep up with the demands. Idiopathic thrombocytopenic purpura in children usually shows up after a viral infection and disappears without a cure after several weeks to months. Symptoms of this disease can appear suddenly (acute type of the disease) or can develop more gradually (chronic). Such symptoms as unexplained bruises, red spots on the skin, blood in the stool, and bleeding from the nose and gums can occur during Idiopathic thrombocytopenic purpura disorder. A physician defines the disease when he or she discovers low platelets count and signs of increased platelet destructions, rather than lowered platelets production in blood and sample from bone marrow. No other causes may be discovered. To cure adults, a physician first tries to suppress the immune responses with large doses of corticosteroid, including Prednisone. Corticosteroid in most cases increases the platelet numbers, but the increase can be transient. Because prolonged use of corticosteroids causes some unwanted effects, the dose should be tapered of promptly. Medications, suppressing immune system including Azathioprine are used, if needed. If medications are not effective or the disease recurs, the surgery called splenectomy (spleen removal) treats the disease in most patients. Large doses of immune globin or anti-rh factor (for patients with RH-positive blood) are injected intravenously to cure patients with acute, possibly fatal bleeding. They are also used for long time, mostly in children to keep platelets counts high enough to avoid bleeding.
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