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Idiopathic hypereosinophilic syndrome is a medical condition, where the count of eosinophils is increasing more than 1,500 cells per blood microliter for more than half a year period without any specific cause. Individuals of any age may develop this syndrome, but it is mostly common in males over the age of 50. The higher count of eosinophils may injure the heart, liver, lungs, nervous system, and skin. For example, the heat may get inflamed in conditions known as Loffler endocarditis, causing blood clots, heart attacks, heart valves, malfunctions, and failure of the heart. The symptoms of Idiopathic hypereosinophilic syndrome depend on which organ is damaged. The symptoms can include fever, weight loss, confusion, coma, pain, weakness, skin rash, stomach pain, chest aches, cough, fatigue, and swelling. The disease is determined when a constant increase count of eosinophils are discovered in patients with these symptoms. Before starting treatment, a physician should confirm, that the eosinophilia is not being resulted from allergic reactions or parasitic infections. If Idiopathic hypereosinophilic syndrome is left untreated, usually more than 80% of individuals with this disease die within 2 years; with a cure, more than 80% survive. Main cause of death is heart damage. Some patients require no treatment other than close observations for a period of 3 to 6 months, but most require treatment using medications, including Hydroxyurea or Prednisone. If these measures of treatment fail, a different medication can be prescribed to be used in combination with a procedure called leukapheresis (removal of eosinophils from the blood).
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