X-Linked Agammaglobulinemia

X-Linked Agammaglobulinemia, called Bruton’s Agammaglobulinemia, affects only boys, and causes absence or reduced numbers of B lymphocytes and extremely low antibodies levels, X Linked Agammaglobulinemia X Linked Agammaglobulinemiabecause of the x-chromosome defect. Infants who have Bruton’s agammaglobulinemia-X-Linked Agammaglobulinemia, progress bones, sinuses, and lungs infections, generally from bacterias, such as streptococcus and hemophilus, and they can progress some unusual brain viral infections.

However, infections usually do not happen until sometime after six month of age because mother’s protective antibodies remain in the infant’s blood until that time. Children, who have X-Linked Agammaglobulinemia may progress polio if they are given oral live polio vaccine. They can also develop arthritis. Immune-globuline infusions or injections are given throughout life to help prevent infections and to provide antibodies. Antibiotics are required if bacterial infections occur. Despite such measures, many boys, who have Bruton’s Agammaglobulinemia develop lung infections and chronic sinuses and also may develop cancer.

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