Wiskott Aldrich Syndrome

Wiskott Aldrich Syndrome affects only boys and results in platelets low number, eczema, and a combined T and BWiskott Aldrich Syndromelymphocytes deficiency, that causes repeated infections. Because the number of platelets is low, bleeding disorders such as bloody diarrhea, can be the early symptom. The deficiency of B and T lymphocytes makes the children susceptible to infections with fungi, viruses, and bacteria.

Respiratory tract infection is common. Children with Wiskott-Aldrich syndrome, who survive past age ten are likely to progress cancers such as leukemia and lymphoma. Surgical spleen removal frequently helps subside the bleeding disorders, because individuals who have Wiscott-Adrich syndrome, low platelets number and these platelets are destroyed in the person’s spleen. Immune globulin infusions and antibiotics can be helpful, but best treatment is bone marrow transplantation.

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