Pheochromocytoma

Pheochromocytoma is a tumor that originates from adrenal glands’ chromaffin cell, resulting in powerful hormones -- catecholamine overproduction that cause high blood pressure and other symptoms.¬† Approximately. in about 20% of Pheochromocytoma cases,¬† the chromaffin cells grow outside their normal adrenal gland location. Only 5% of Pheochromocytomas Pheochromocytoma 300x225 Pheochromocytomathat grow within the adrenal gland are cancerous, but 30% of those outside the adrenal gland are cancerous. The tumor occurs in about 1 in 1000 individuals.

Pheochromocytoma (tumor) can occur in males and females at any age, but it is most likely to appear between ages thirty and sixty. Pheochromocytoma  is generally very small and it rarely result in symptoms from obstruction or pressure, and commonly can not be felt by doctors. The main Pheochromocytoma symptom is high blood pressure, which can be extremely severe. In roughly 50% of the individuals with this disease, the persistant high blood pressure occurs. In the remaining, the high blood pressure comes and goes; in some cases triggered by emotional trauma, pressure on tumor, medications, massage, and on rare ocasion-the urination simple act.

Other symptoms of Pheochromocytoma may include all or any of the following: constipation, pounding and fast heart rate, impending doom odd sense, excessive sweating, finger tingling, light headedness when standing, visual disturbance, rapid breathing, vomiting, flushing, nausea, stomach and chest pain, and severe headaches. A doctor may suspect a Pheochromocytomas because about 50% of individuals experience no symptoms other than high blood pressure. However, the doctor can order specific laboratory tests, if high blood pressure exist in a young individuals, comes and goes, or is accompanied with other Pheochromocytoma’s symptoms. For instance, specific catecholamines level can be measured in a urine sample. MRI(magnetic resonance imaging) and CT(computed tomography) scans may help find Pheochromocytoma. The best treatment of Pheochromocytomas is the removal of tumor surgically. Surgery is frequently delayed, however, until a surgeon may bring the secretion of tumor under control with drug, because having high catecholamines level, may be dangerous during operation. Prescription drugs such as Propranolol and Phenoxybenzamine are usually given together, and medication Metyrosine or other drugs are frequently prescribed to keep blood pressure under control. If the Pheochromocytoma is a cancer that had spread, Dacarbazine, Vincristine, and Cyclophosphamide can help slow the growth of tumor.

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