Celiac Disease (seliac sprue, gluten enteropathy, nontropical sprue) is an inherited medical condition, where an allergic intolerance to a protein-gluten results in the changes of the person’s intestine that causes malabsorption.
Approx. one in three hundred individuals in Southwestern Ireland and one in five thousands in North America have Celiac Disease. Such hereditary disorder resulted from a sensitivity to protein-gluten, is found in rye and wheat, as well as oats and barley. In Celiac disease, gluten molecules’ part combine with antibodies in the person’s small intestine, resulting in the intestine normal brush-like lining to flatten, causing smooth surfaces to reduce absorbtion and digesting food.
When food consisting protein-gluten is avoided, the healthy brush-like surface is commonly restored and healthy intestinal functions returns. Celiac Disease can start at any age. In infants, no symptoms occur until food consisting of gluten is first eaten. The disease frequently does not result in fatty stool or diarrhea, and children can experience only mild symptoms similar to those of a simple stomach upset. However, some children have painful abdominal bloating, start pass bulky, foul-smell, pale stool and stop grow normally. Anemia progresses from lack of iron. If the protein level in blood falls significantly low, the children retain fluid, and tissue can swell (called edema).
In some individuals, symptoms do not occur until adulthood. The deficiency of nutrients causing by malabsorbtions in Celiac Disease may result in more symptoms, which include leg-arm pins-and-needles sensations, bone pain and weight loss. Some individuals with Celiac Disease, developed in childhood, can have abnormally long bowed bones. Depending on duration and severity of this disorder, an individual can have low blood level of sodium, potassium, calcium or protein. Prothrombin deficiency, which is essential in blood clotting causes prolonged bleeding after the injuries and easy bruising. Girls who have Celiac Disease might not have menstrual periods.
The doctor suggests Celiac Disease when he or she sees a pale children with wasted buttocks and a pot-belly despite eating proper diet, particularly if there is a family Celiac Disease history exists. Results of X-Ray and laboratory tests can help doctor to determine diagnosis. Laboratory tests that measure Xylose (a simple sugar) absorbtion sometimes used.
The diagnosis of Celiac Disease confirmed by testing of specimen’s biopsy that show a small intestine’s flattened lining and lining improvement after an individual stops eating gluten products. The treatment of Celiac Disease consists of avoiding gluten product intake. In some cases, the child who is seriously sick when first diagnosed with Celiac Disease, requires an intravenous feeding period. Sometimes, adults also need such feeding.
A Gluten-free diet significantly improves prognosis for adults and children. However, Celiac Disorder may be fatal, especially in adults with severe type. Sometimes, adults with Celiac Disease can develop lymphoma form of cancer in the intestine.